Autonomic Dysfunction

Hypermobile Ehlers Danlos Syndrome (hEDS) is an autosomal dominant connective tissue disorder without a known genetic cause that disproportionately affects women. Though this sex differential is recognized clinically, little research has been done to demonstrate the biological association between sex hormones and the presentation of symptoms in hEDS. This study assesses variations in sex hormones and daily symptoms to address which hormones may be contributing to increased symptom severity.